Located in the Sacramento area, Lake Natoma is a notable spot for fishing, particularly for catching big rainbow trout. As an afterbay of Folsom Lake, Lake Natoma regularly produces some of the largest rainbow trout in the state.

The thriving population of rainbow trout in the lake benefits from the abundance of pond smelt and other feed channeled in by the hydro-electric turbines of Folsom Dam. The Department of Fish and Game ensures regular stocking, and the lake is home to large resident trout which prey on the newly stocked ones. While Lake Natoma has a sizable trout population, it also presents reasonable bass fishing in the summer. But for those keen on bass and other warm-water species, Folsom Lake is typically the preferred destination.

While boating is welcome on Lake Natoma, be aware of the enforced 5 mph speed limit. Waterskiing isn't allowed, and motors are restricted from use in the lake's lower half.